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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering With G6pdd. Which Citrus Fruits Are Recommended?

hi! i am maha from pakistan. my cousin is suffering from G6pdd and i want to ask a question regarding this disease. i studied that ascorbic acid must be avoided by these patients but on the other hand antioxidants like citrus fruits (lemon,oranges,pineapple etc) are necessary for g6pdd patients. now i am quite confuse what to do? because these fruits contain ascorbic acid. kindly guide me whether to take these friuts or not in g6pdd?
Sat, 10 Nov 2012
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Pediatrician, Neonatology 's  Response
Hi Maha
Let me clear your misunderstanding. Ascorbic Acid or Vitamin -C is not forbidden for G6PD (Glucose-6-Phosphate Dehydrogenase) deficient person. There are a few reported cases of Hemolysis in G6PD deficient individual with Very High dose of Ascorbic acid. But remember - 'VERY HIGH DOSE'. That is why Vitamin-C / Ascorbic acid is not enlisted in forbidden medicine list for G6PD deficient individual.

Glucose-6-Phosphate Dehydrogenase is an enzyme, deficiency of which make Red Blood Cells (RBC) labile to oxidative damage, resulting in hemolysis. Antioxidant rich foods can supply the antioxidants which fight oxidative stress and protect RBC.

As I already mentioned, ascorbic acid is not banned for G6PD deficient individual. So, citrus foods in low quantity will not cause any harm to G6PD deficient individual.
Foods that are richest in antioxidants are - berries (sour cherries, blackberries, raspberries, blueberries and black currants), cereals (oats, barley, millet or corn), vegetables (peppers, artichokes, kale, brussels sprouts, spinach, parsley and red cabbage), roots (Ginger and red beet roots ), seeds and nuts (sunflower seeds and walnuts). These foods are good for G6PD deficient person.

Hope I could make it clear. Feel free to post if you have other queries.
For complete guidance of dietary and medicinal restrictions, please consult your doctor.
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Suffering With G6pdd. Which Citrus Fruits Are Recommended?

Hi Maha Let me clear your misunderstanding. Ascorbic Acid or Vitamin -C is not forbidden for G6PD (Glucose-6-Phosphate Dehydrogenase) deficient person. There are a few reported cases of Hemolysis in G6PD deficient individual with Very High dose of Ascorbic acid. But remember - VERY HIGH DOSE . That is why Vitamin-C / Ascorbic acid is not enlisted in forbidden medicine list for G6PD deficient individual. Glucose-6-Phosphate Dehydrogenase is an enzyme, deficiency of which make Red Blood Cells (RBC) labile to oxidative damage, resulting in hemolysis. Antioxidant rich foods can supply the antioxidants which fight oxidative stress and protect RBC. As I already mentioned, ascorbic acid is not banned for G6PD deficient individual. So, citrus foods in low quantity will not cause any harm to G6PD deficient individual. Foods that are richest in antioxidants are - berries (sour cherries, blackberries, raspberries, blueberries and black currants), cereals (oats, barley, millet or corn), vegetables (peppers, artichokes, kale, brussels sprouts, spinach, parsley and red cabbage), roots (Ginger and red beet roots ), seeds and nuts (sunflower seeds and walnuts). These foods are good for G6PD deficient person. Hope I could make it clear. Feel free to post if you have other queries. For complete guidance of dietary and medicinal restrictions, please consult your doctor.