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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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Suffering From Mitral Valve Prolapse, PSVT And Syncope, Fatigue And Enervation With Hard Performance, Taken Pendolol. Is It Safe To Work At Full Speed?

I am a performing art student with mitral valve prolapse , psvt, and syncope . For the longest time when I would perform the week or so after I would not be able to move. My body would be too tired to let me leave my bed. I would also often faint when pushing my self too hard in performance. Almost a year ago I was put on Pendolol to combat this. Now I am afraid the fatigue from the medication has proved nearly worse for me. I have had to give up performing altogether as I can now no longer perform at even half the energy I could before. I want this to be my career, but I don t know if coming off medication is really safe at this point.
Thu, 22 Aug 2013
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Cardiologist 's  Response
Dear patient,

Thanks for your health concerns. I agree that if you see a big difference in terms of your fatigue after starting pendolol, it is a possibility to consider that the medication could actually be contributing to the fatigue. This is a well described side effect for B Blockers. Discontinuing a beta blocker abruptly indeed carries risks of rebound side effects, so the medication has to be weaned off gradually or substituted by another type of B blocker. My suggestion in patients with your symptoms would typically be atenolol, which does not act on the nervous system.


Truly yours,

Dr Brenes-Salazar MD
Cardiology
Mayo Clinic MN
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Suffering From Mitral Valve Prolapse, PSVT And Syncope, Fatigue And Enervation With Hard Performance, Taken Pendolol. Is It Safe To Work At Full Speed?

Dear patient, Thanks for your health concerns. I agree that if you see a big difference in terms of your fatigue after starting pendolol, it is a possibility to consider that the medication could actually be contributing to the fatigue. This is a well described side effect for B Blockers. Discontinuing a beta blocker abruptly indeed carries risks of rebound side effects, so the medication has to be weaned off gradually or substituted by another type of B blocker. My suggestion in patients with your symptoms would typically be atenolol, which does not act on the nervous system. Truly yours, Dr Brenes-Salazar MD Cardiology Mayo Clinic MN