Hi mam thanks for the query.
From the complaints you had outlined regarding your knee it could be osteoarthritis
of the knee (Wear and tear ) and also similar changes in the spine (Spondylosis
). It is not only with medications that you may feel better but also I advice you to learn some knee strengthening exercises from local physiotherapist. Take a advice from you local orthopaedic doctor to reduce the usage of sustained release pain medication, and also ask him about the local pain reliving gels and any other modalities of pain management.