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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is There Any Relation Between Hepatitis B And Hepatitis Shots?

I took the series of hepatitis shots. a few days after I took the last in the series I donated blood. I received a letter from the blood center that I tested positive for hepatitis B. Could this be in relation to the shot? My family MD is on vacation and I am very concerned.
Fri, 6 Feb 2015
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Pain Medicine & Palliative Care Specialist 's  Response
Hi there,
Thanks for posting your query.
A person is said to positive for Hepatitis B if his blood is positive for HBsAg and Anti HBc antibodies. When a person donates blood these two are also tested to see if he is infected with hepatitis B virus.

Hepatitis B shots do not lead positive HBsAg and Anti-HBc.
The only marker that becomes positive after hepatitis B shots is anti-HBs.
Presence of more than 10 IU/ml of anti-HBs indicates you are protected against hepatitis B.

In your case it looks like you are positive for HBsAg. It is likely that you had this infection even before you got the hepatitis shots.
So the reason for your positive hepatitis B is past infection and not the hepatitis shots.

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Is There Any Relation Between Hepatitis B And Hepatitis Shots?

Hi there, Thanks for posting your query. A person is said to positive for Hepatitis B if his blood is positive for HBsAg and Anti HBc antibodies. When a person donates blood these two are also tested to see if he is infected with hepatitis B virus. Hepatitis B shots do not lead positive HBsAg and Anti-HBc. The only marker that becomes positive after hepatitis B shots is anti-HBs. Presence of more than 10 IU/ml of anti-HBs indicates you are protected against hepatitis B. In your case it looks like you are positive for HBsAg. It is likely that you had this infection even before you got the hepatitis shots. So the reason for your positive hepatitis B is past infection and not the hepatitis shots. Is this answer helpful?