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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Taking Comtan Along With Mirapex Safe While Treating Parkinson S Disease?

I was diagnosed with Parkinson s7 years ago and up until recentlyMirapex & sinemet mostly took care of walking problem, I have recently had 2 major back surgeries and my mobility deteriorated even after going through rehab & physical therapy. My neurologist has prescribed Comtan3 X daily. My sinemet went from 2 X daily to 4 X daily. My mirapex remains same at 4 X daily My question is do I take the Comtan at same time as sinemet or does it matter how I take it?Thank you.
Wed, 29 Aug 2018
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Neurologist, Surgical,  's  Response
Hi,

There are no serious interactions that may result in adverse effects between Comtan (Entacapone), Mirapex (Pramipexole) and Sinemet (Carbidopa/Levodopa ).

Comtan should be taken with every dose of Sinemet simultaneously.

So, I think you should discuss with your Neurologist for changes in the schedule of taking Sinemet and Comtan.

Hope I have answered your query. Let me know if I can assist you further.

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Is Taking Comtan Along With Mirapex Safe While Treating Parkinson S Disease?

Hi, There are no serious interactions that may result in adverse effects between Comtan (Entacapone), Mirapex (Pramipexole) and Sinemet (Carbidopa/Levodopa ). Comtan should be taken with every dose of Sinemet simultaneously. So, I think you should discuss with your Neurologist for changes in the schedule of taking Sinemet and Comtan. Hope I have answered your query. Let me know if I can assist you further.