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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Strong Musky Smell In Urine Normal While Taking Methotrexate?

My name is Judy. My question has to do with a strong urine smell. I never noticed it before. I am 170 lb. 67 yes. Taking Methotrexate for RA. Taking 6-2.5 mg tablets every Friday w breakfast. Started April 10th. Have noticed a strong musky smell in urine. Is that to be expected¿
Thu, 28 Apr 2022
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Cardiologist 's  Response
Hello,

The smell in the urine is a common adverse effect of Methotrexate. I recommend taking folic acid to reduce the smell and performing a urine bacterial culture, just to be sure that there is no infection.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Ilir Sharka, Cardiologist
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Is Strong Musky Smell In Urine Normal While Taking Methotrexate?

Hello, The smell in the urine is a common adverse effect of Methotrexate. I recommend taking folic acid to reduce the smell and performing a urine bacterial culture, just to be sure that there is no infection. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Ilir Sharka, Cardiologist