Hello, Thanks for writing your query to us. Melasma is dark skin discoloration, which particularly occurs in women. Meladerm skin whitening cream is a natural product. This melasma treatment makes use of natural products and ingredients such as licorice extract, lemon juice extract, mulberry extract, vitamin B3 and emblica powder. All these ingredients are naturally extracted and used to produce the skin whitening cream. The cream helps in reducing the production of melanin. Melanin is a substance formed due to excessive skin exposure in the sun, and the Meladerm melasma treatment helps to obstruct the formation of melanin. Use of Meladerm for melasma treatment is not without side effects. Depending on how your skin reacts to the natural ingredients, the cream can cause mild irritation sometimes. Consult with your doctor first and know about your skin type. A doctor will be able to tell you whether the ingredients of the Meladerm treatment can cause any skin problems or not. Take care.