Hello, Thanks for using Healthcaremagic. i had gone through all the data you have posted. This day our era of medicine is Evidence based medicine there is little rolefor empirical therapy. here we try to prove what we are treating, only if every test comes out negative then we go for emperical treatment when clinical suspicion is very high. if suspicion of Tuberculosis is high sputum for AFB, Chest x ray,ESR,Mantoux test are baseline if negative but suspicion is high bronchoscopy or lymphnode biopsy if any palpable lymphnode is seen or CT chest if some doubt exists. DOTS is an effective medicine, contains combination of antibiotics against Tuberculosis bacteria. main side effectof ATT( anti tuberculosis therapy) is hepatitis,neuropathy, nausea,vomiting and ethambutol is relatively contraindicated in pregnancy. so if she dosent have the disease we are placing her at risk of these side effects due to these drugs.rarely ATT induced hepatitis may lead to fatal liver failure..so better to confirm the diagnosis Hope this helps..