Is crisanta helpful for those showing signs of pcos? I have acne not responding to topical treatment. And I didn't want to take oral tretinoin.i started developing hair loss also from one side of scalp.my scan didn't show pcos.a gynaec told me to start crisanta-ls. I had spotting outside my dates.so she told to have crisanta. Acne does reduce after months of use.but is it causing any harm in the long run? Two years back I had it for 8months continuously. Now I've had for 3months already since my acne flare up started again which didn't respond to any acne treatment.