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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Abieraterone Safe To Take For Prostate Cancer?

my husband has advance prostate cancer for 3 years, recently he s been on new drug Abieraterone for 6 months, all stabled untill now, he has bruises appeared on his hands and legs for no resons and a little tired then normal! please can you tell why? is it urgent to be seen by oncologist asap? thank you.?
Mon, 19 May 2014
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Oncologist 's  Response
Bruises without trauma usually indicates an underlying clotting insufficiency. It can be due to low platelet count (platelets are responsible for clotting blood). Although abiraterone is not known for decreasing blood cell count but this possibility should be ruled out.
The other possibility is prostate cancer progression affecting marrow and blood counts.
The tiredness can be secondary to disease progression OR mineralocorticoid deficieny or hypokalemia (low potassium levels) associated with abiraterone.
Please discuss this with your treating oncologist. An early appointment is suggested.
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Is Abieraterone Safe To Take For Prostate Cancer?

Bruises without trauma usually indicates an underlying clotting insufficiency. It can be due to low platelet count (platelets are responsible for clotting blood). Although abiraterone is not known for decreasing blood cell count but this possibility should be ruled out. The other possibility is prostate cancer progression affecting marrow and blood counts. The tiredness can be secondary to disease progression OR mineralocorticoid deficieny or hypokalemia (low potassium levels) associated with abiraterone. Please discuss this with your treating oncologist. An early appointment is suggested.