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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is Mexate Available In The US?

Is Mexate available in the U.S.? I am a Medical Assistant student and I am generating drug cards for my Pharmacology class, and I cannot find Mexate in my reference books. The questions I need to provide on my drug cards are the following: Generic name; Classification; Pregnancy Category; Indications; Therapeutic Effects; Contradictions; Adverse Reactions; Adult Route/Dose; Pediatric Route/Dose; Patient Education. Do you know where the best place to locate this information?
Tue, 13 Dec 2016
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General & Family Physician 's  Response
Hi,
Thanks for posting in HCM.
I understand your concern.
Mexate Tablet contains 'Methotrexate' as an active ingredient.
Classification: It is an 'Antimetabolite'. It competes with folic acid uptake in cells, thus altering DNA replication and cell division. It causes stopping the growth of cells in tumors and decreasing the activity of the immune system.
Possible Side Effects of Methotrexate include: Nausea and/or Vomiting, Diarrhea, Mouth Ulcers, Low White Blood Cell Count, Low Red Blood Cell Count, Low Platelet Count, Fatigue, Loss or Thinning of Scalp and Body Hair and Sensitivity to light.
Contraindications
Hypersensitivity to Mexate is a contraindication. In addition, it should not be taken if the following conditions are present:
1. Alcoholic liver disease
2. Blood disorders
3. Neoplastic diseases
4. Pregnant women
5. Thrombocytopenia
Uses: Mexate Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:
(a) Rheumatoid arthritis
(b) Cancers of breast
(c) Skin cancer
(d) Head and neck cancer
(e) Lung cancer
(f) Psoriasis.
Dosage: Depends on the underlying condition which is being treated. Usual dose is 10mg administered everyday or once a week.
It is available under various trade names.
Hope the information provided would be helpful.
All the best.
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Is Mexate Available In The US?

Hi, Thanks for posting in HCM. I understand your concern. Mexate Tablet contains Methotrexate as an active ingredient. Classification: It is an Antimetabolite . It competes with folic acid uptake in cells, thus altering DNA replication and cell division. It causes stopping the growth of cells in tumors and decreasing the activity of the immune system. Possible Side Effects of Methotrexate include: Nausea and/or Vomiting, Diarrhea, Mouth Ulcers, Low White Blood Cell Count, Low Red Blood Cell Count, Low Platelet Count, Fatigue, Loss or Thinning of Scalp and Body Hair and Sensitivity to light. Contraindications Hypersensitivity to Mexate is a contraindication. In addition, it should not be taken if the following conditions are present: 1. Alcoholic liver disease 2. Blood disorders 3. Neoplastic diseases 4. Pregnant women 5. Thrombocytopenia Uses: Mexate Tablet is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms: (a) Rheumatoid arthritis (b) Cancers of breast (c) Skin cancer (d) Head and neck cancer (e) Lung cancer (f) Psoriasis. Dosage: Depends on the underlying condition which is being treated. Usual dose is 10mg administered everyday or once a week. It is available under various trade names. Hope the information provided would be helpful. All the best.