Hi ! Good morning. I am Dr Shareef answering your query. Yes, this combination of a proton pump inhibitor and a prokinetic agent along with a locally acting antacid is known to be a good one. You might have to continue the medications for a long period to achieve a good long lasting effect. However, the following few suggestions might help you more in minimizing your requirement of medicines : 1) Elevate the head end of the bed with two blocks on each side, so that the regurgitation does not occur while lying down, and the contents of esophagus and stomach flow down with gravity. 2) Some modification in your diet like more of roughage, enough liquids, avoidance of oily, fried, and fast food. Avoidance of smoking and alcoholic beverages are proved to be of definitive help. 3) Regular routine exercises like morning walk depending on your medical fitness. I hope this information would help you in discussing with your family physician/treating doctor in further management of your problem. Please do not hesitate to ask in case of any further doubts. Thanks for choosing health care magic to clear doubts on your health problems. Wishing you an early recovery. Dr Shareef.