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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Is 15mg Of Clorazepate Thrice A Day Fatal?

I have been prescribed 8mg per 4-6 hours and 15mg of Traxene (Clorazepate) as well. I have read that the two can interact with each other and it was the drug combination that ultimately lead Heath Ledger to his death, except he was using Oxycodone. How much of each is too much. I just had nasal reconstruction and a septoplasty and just got the stints taken out today, but the doctor refilled my prescription as he could tell I was still in a good amount of pain. I am to take 7.5 to 15mg of the Clorazepate 3 times of day, or as needed for panic and anxiety attacks as I have PTSD. What are your recommendations and how much would be a fatal dose. As I am in bed most of the day, although I am moving around more now, all I do is sit and think about taking too much and someone finding me overdosed from taking too much. Is there a specific dosage at my weight 130lbs that I should stick to? The pain does get worse and I will occasionally take 1 or 2 more in between those 4 to 6 hours. Same with the Clorazepate, I may split up the dosages, but I don t take more than prescribed on that drug.
Wed, 5 Sep 2018
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General Surgeon 's  Response
Hi,

As per the FDA guidelines, the maximum dosage of 60 mg in divided doses can be safely given when consumed alone.

In combination with Oxycodone, the dosage has to be adjusted as per the case, in general it should be around 30-45 mg. So under medical supervision, it does not sound to be fatal.

Hope I have answered your query. Let me know if I can assist you further.
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Is 15mg Of Clorazepate Thrice A Day Fatal?

Hi, As per the FDA guidelines, the maximum dosage of 60 mg in divided doses can be safely given when consumed alone. In combination with Oxycodone, the dosage has to be adjusted as per the case, in general it should be around 30-45 mg. So under medical supervision, it does not sound to be fatal. Hope I have answered your query. Let me know if I can assist you further.