Hi Thanks for posting your query on HCM. I appreciate your concern for the gall stones. Incomplete data; Age, gender any associated medical illness? Medication (Decolic) you take by mouth may help dissolve gallstones. But it may take months or years of treatment to dissolve your gallstones in this way. Since there is no response from the medication that you have been taking so far, so you need to consult a surgeon for proper evaluation and a possible surgical removal of the gall bladder with the multiple stones. Once your gallbladder is removed, bile flows directly from your liver into your small intestine, rather than being stored in your gallbladder. The gallbladder removal doesn t affect your ability to digest food. Hope this answers your query. A feed back is appreciated.