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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How To Treat CVID,chronic Cough Andwith Biopsy Report: Elevated Cellular Inflammation And High Lipid Macrophages?

Young daughter with CVID had a lung biopsy, history of chronic cough and rattles in lung. Has not responded to oral steroids, antibiotics or albuterol. Biopsy came back with cells high inflammation and high lipid macrophages. Bacterial and fungal cultures still negative. Rest pending with lab still. The things that are positive seem non specific, so finding cause is still there..what are possibilities?
Mon, 3 Feb 2014
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General & Family Physician,  's  Response
Hi, thank you for posting.

CVID syndrome is a genetic immunodeficiency disease. Causes of this syndrome are still unknown.
The treatment for this syndrome is complex and it requires the collaboration of some medical specialties, where the main specialist is immunologist.

This syndrome is mainly treated with IVIG(Intravenous immunoglobulin). IVIG is a blood product that contains polyvalent immunoglobulin.

You can find this product with a lot of trade names, one is Gamunex.

The dosage of IVIG is 100-400mg/kg of body weight. It is implemented every
3-4 weeks.

*You have to contact an immunologist.

Dr. Behar.
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How To Treat CVID,chronic Cough Andwith Biopsy Report: Elevated Cellular Inflammation And High Lipid Macrophages?

Hi, thank you for posting. CVID syndrome is a genetic immunodeficiency disease. Causes of this syndrome are still unknown. The treatment for this syndrome is complex and it requires the collaboration of some medical specialties, where the main specialist is immunologist. This syndrome is mainly treated with IVIG(Intravenous immunoglobulin). IVIG is a blood product that contains polyvalent immunoglobulin. You can find this product with a lot of trade names, one is Gamunex. The dosage of IVIG is 100-400mg/kg of body weight. It is implemented every 3-4 weeks. *You have to contact an immunologist. Dr. Behar.