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How risky is it to donate a kidney? How is the after life for donor?

A relative of mine is in 10th Std who needs kidney (ill from around a year). His uncle is aged 55 yrs old without any health problems. Aunty is 52 but a diabetic patient. Also suffering from arthritis. She is scared to ask her husband to donate kidney for his nephew. Is it risky for donor or how would it be for his remaing life after donating kidney. Can you suggest or rather tell me whether there is any risk?

Mrs. Thakur(a relative)
Asked On : Thu, 28 Mar 2013
Answers:  1 Views:  25
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Diseases and Conditions
Internal Medicine Specialist 's  Response

According to the Cleveland Clinic, kidney donors are at no greater risk for future health problems than those with two kidneys. Kidney donation also does not change life expectancy for the donors.

After kidney donation remaining kidney gets enlarged and and is sufficient to compensate for the work of two kidneys and the donor can live productive life there after.

There is no direct incidence of complications after kidney donation hence i would like to give one standard reference that could help you more.

Long-Term Consequences of Kidney Donation:
Hassan N. et al.
N Engl J Med 2009; 360:459-469January 29, 2009DOI: 10.1056/NEJMoa0804883.

Results of the study are as follows:
The survival of kidney donors was similar to that of controls who were matched for age, sex, and race or ethnic group. ESRD (End stage renal disease) developed in 11 donors, a rate of 180 cases per million persons per year, as compared with a rate of 268 per million per year in the general population. At a mean (±SD) of 12.2±9.2 years after donation, 85.5% of the subgroup of 255 donors had a GFR of 60 ml per minute per 1.73 m2 of body-surface area or higher, 32.1% had hypertension, and 12.7% had albuminuria. Older age and higher body-mass index, but not a longer time since donation, were associated with both a GFR that was lower than 60 ml per minute per 1.73 m2 and hypertension. A longer time since donation, however, was independently associated with albuminuria. Most donors had quality-of-life scores that were better than population norms, and the prevalence of coexisting conditions was similar to that among controls from the National Health and Nutrition Examination Survey (NHANES) who were matched for age, sex, race or ethnic group, and body-mass index.
Survival and the risk of ESRD in carefully screened kidney donors appear to be similar to those in the general population. Most donors who were studied had a preserved GFR, normal albumin excretion, and an excellent quality of life.

For detail information you can to the above mentioned reference.

Hope this could help you.

Answered: Fri, 29 Mar 2013
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