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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Long Does Melatonin Stay In The System?

I took 5mg melatonin and couldn t sleep so later drank some red wine - I broke out in very painful hives that moved all over my legs and back. I thought it was suddenly the sulphites so I got some chardonnay next day. I didn t take any melatonin and drank only 2 small glasses but got hives again, not as severe, but still. Last night I figured the melatonin must be out of my system, so I had just a small glass of chardonnay and my lips swelled and I got a few hives on my arm and chest. How long before this is out of my system, please? I don t have health care or any money...please help me?
Mon, 15 Mar 2021
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General & Family Physician 's  Response
Hi,

Melatonin stays in the body average 5 hours (2.5-10 hours) depending on the dose and numerous other factors. The sleep inducing tendency of melatonin depends on the sleeping environment also besides dose of melatonin. A dim lighted, cool and noiseless environment helps to act melatonin faster. Though hives as well as lip swelling both can be symptoms of allergy, but in your case it does not seem due to melatonin, rather any other cause like alcohol, some food or some room freshener, perfume etc., may be cause for this.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Satnarain Bansal, General & Family Physician
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How Long Does Melatonin Stay In The System?

Hi, Melatonin stays in the body average 5 hours (2.5-10 hours) depending on the dose and numerous other factors. The sleep inducing tendency of melatonin depends on the sleeping environment also besides dose of melatonin. A dim lighted, cool and noiseless environment helps to act melatonin faster. Though hives as well as lip swelling both can be symptoms of allergy, but in your case it does not seem due to melatonin, rather any other cause like alcohol, some food or some room freshener, perfume etc., may be cause for this. Take care. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Satnarain Bansal, General & Family Physician