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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Effective Is AKT1 For Spine Tb?

Helli Doc, my wife is of age 32 and suffring from spine tb. her weight is 70 kg..and heigh 5 7 . She is taking AKT4 for the last 10 days. One of our family doc suggest AKT1 insteadof AKT4 since her weight is 70kg. Could you please suggest which is a better option Thank You Sanjeet Singh
Tue, 11 Aug 2015
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Internal Medicine Specialist,  's  Response
Hello....
Tuberculosis of spine needs at least 9 months to 1 year course of Anti tubercular therapy.
According to regime, start with 4 line drugs as Intensive therapy then switch over to 2 line drugs as Maintenance therapy. In short form written as: 2(HRZE) with 7-10 (HR). In this H: Isoniazide, R: Rifampicin, Z: Pyrizinamide, E: Ethambutol.
As in common ATT drugs are in market is AKT. Accordig to my knowledge AKT 1 means only Isoniazide, AKT2 means Isoniazide with Rifampicin, AKT3 means Isoniazide+Rifampicin+Pyrizinamide, AKT4 means all four HRZE.
Because You just started AKT 4 since 10 days. So according to guideline you have to take AKT 4 at least for 2 months then take AKT 2 for 7 to 10 months according to your clinical response.
So in my opinion you can continue on AKT 4 at present, at least for 2 months.

Thank You
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How Effective Is AKT1 For Spine Tb?

Hello.... Tuberculosis of spine needs at least 9 months to 1 year course of Anti tubercular therapy. According to regime, start with 4 line drugs as Intensive therapy then switch over to 2 line drugs as Maintenance therapy. In short form written as: 2(HRZE) with 7-10 (HR). In this H: Isoniazide, R: Rifampicin, Z: Pyrizinamide, E: Ethambutol. As in common ATT drugs are in market is AKT. Accordig to my knowledge AKT 1 means only Isoniazide, AKT2 means Isoniazide with Rifampicin, AKT3 means Isoniazide+Rifampicin+Pyrizinamide, AKT4 means all four HRZE. Because You just started AKT 4 since 10 days. So according to guideline you have to take AKT 4 at least for 2 months then take AKT 2 for 7 to 10 months according to your clinical response. So in my opinion you can continue on AKT 4 at present, at least for 2 months. Thank You