respected user, hi I evaluated your query thoroughly. Surely you can change to E45 along with taking more extra precautions like gentle sponging of face rather than rubbing avoid direct exposure to sunlight without sunscreen always cover face with clean cotton clothes when outside avoid excess oily / spicy / non vegetarian stuffs till possible avoid smoking / alcohol if consuming maintain hydration all times with plenty of liquids consume more citrus containing fruits balance nutritious diet with rich anti-oxidants,vitamins,minerals,trace elements avoid stress / anxiety regular sound sleep of 8 hours walking in fresh air with ozone intake , deep breathing exercises, YOGA help to great extent Hope this helps you Wishing you fine glory of face today & always. Regards dear.