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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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How Can Anaphylaxis Shock Be Avoided While Taking Medications?

HI IAM DR NIDHI AGARWAL (OBS &GYANE) I DIDN T HAVE ANY HISTORY OF ALLERGY .2 YRS BACK I SUDDENLY HAD SEVERE ANAPHYLACTIC SHOCK WITH CEFAUROXIME(CEFTUM) AND AGAIN AFTER 2 MTH WITH ONDEM NOW IAM AFRAID TO TAKE ANY MED.WHOM TO CONSULT.I AM RESIDING IN DELHI
Thu, 14 Aug 2014
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Allergist and Immunologist,  's  Response
Hello Dr Nidhi Agarwal,

Thank you for asking at HCM.

I went through your history and would like to make following suggestions to you:

1. Both cefuroxime and ondansetron are known to cause severe allergic reactions like anaphylaxis.

2. It is also possible that not the drug itself, but preservatives, excipients, coloring agents, etc used in manufacturing the drug can also cause anaphylaxis.

3. There are not very reliable tests available to definitely diagnose or rule out drug allergies except in case of penicillin allergies. Hence, once a patient had an anaphylaxis to a particular drug, the best way it to avoid it.

4. I would suggest you to consul an Allergist-Immunologist in Delhi who will ask your history in great detail to come to certain conclusion.

5. There are many allergists in Delhi. You can consult the one who is experienced and also the one who is closer to your place. VP Chest Institute in Delhi has a department that specially deals with Allergy-Immunology and has many renowned allergists. Hope they may e helpful to you.

Should you have any other concern, please feel free to ask at HCM.

Wish you the best of the health.

Thank you & Regards.
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How Can Anaphylaxis Shock Be Avoided While Taking Medications?

Hello Dr Nidhi Agarwal, Thank you for asking at HCM. I went through your history and would like to make following suggestions to you: 1. Both cefuroxime and ondansetron are known to cause severe allergic reactions like anaphylaxis. 2. It is also possible that not the drug itself, but preservatives, excipients, coloring agents, etc used in manufacturing the drug can also cause anaphylaxis. 3. There are not very reliable tests available to definitely diagnose or rule out drug allergies except in case of penicillin allergies. Hence, once a patient had an anaphylaxis to a particular drug, the best way it to avoid it. 4. I would suggest you to consul an Allergist-Immunologist in Delhi who will ask your history in great detail to come to certain conclusion. 5. There are many allergists in Delhi. You can consult the one who is experienced and also the one who is closer to your place. VP Chest Institute in Delhi has a department that specially deals with Allergy-Immunology and has many renowned allergists. Hope they may e helpful to you. Should you have any other concern, please feel free to ask at HCM. Wish you the best of the health. Thank you & Regards.