Thanks for writing to us.
Briefly,the high eosinophilia could be caused by intestinal worms infestation /allergy
to helminthic toxins released by worms/pulmonary/tropical eosinophilia
. Due to availability of reports only and no clinical examination courtesy the internet ,the doctors scope is left to D/D or Differential Diagnosis.
The eosinophilia in Coastal areas ,in addition to worms could be also due to Filariasis
,the vector spreading the same is mosquito.
Meanwhile a Stool microscopy to confirm the presence of Ova and Cysts of Worms and a Midnight Blood Sample for confirming Microfilaria
can be done in a recognised Lab.
The treatment can be started with Tab Albendazole(Combatrin-A or Zentel) 400 mg at night for 01 day followed by T.Hetrazan
(Di Ethyl carbamazine)50 mg PO once -Day 01st day
T.Hetrazan 50 mg 02 nd Day and 2 TID/100mg thrice daily for 04 to 14 days and then repeat the Eosinophil count
The allergic symptomatic treatment can be given with Levo-Cetzine/Cetzine-05 mg BID.
The gastrointestinal side effects such as Nausea/Hyperacidity
can be kept under check with T.Zinetac300 mg taken before breakfast .
Usually the Eosinophilia resolves within 21 days of therapy with Hetrazan at the most and the differential eosinophil count drops to 0-1%.
Wishing you a quick recovery.
Dr Lt Cdr ASN Bhushan,