Hello saurabh, greetings from healthcaremagic.com I am Dr Sourav Chakraborty and i have seen the case scenario of your mother and will help you out with your query. Your mother hasbeen diagnosed with high creatinine levels recently less than a year , you have not mentioned her blood urea and uric acid levels which is very important in your mother s case. Also i would like to enquire about her co morbid conditions like diabetes , because we have to rule out any medicinal cause of increase in creatinine. You have not mentioned the age of your mother but if she is less than 50 years then please get ultrasonography of whole abdomen with renal doppler study , which will rule out any structural abnormality. We have to be sure it is primarily a kidney disease and not secondary to other cause, as if your other have kidney disease then she has to lead very disciplined life also need a lot of support from family members. If she is an established case of chronic kidney disease i ask you to restrict protein in her as it may lead to increase in creatinine. The medicines you mentioned about are new supportive medicine which is used to renal health . Although no substantial trials have been publishes , small trials with some patients have revealed it to be beneficial in preserving kidney function and prevent further damage. There is lot to discuss about kidney disease and i have tried to give some idea relevant to your mom. For more information discuss with her doctor. Hope io have been lucid in her approach. Take care