hello dear thanks for your query at HCM i undertand your concern your son is diagnosed with lyme disease. this is natural course of the lyme disease Early localized : 3-30 days Erythema, variable constitutional symptoms (headache, fever, myalgia, arthralgia, fatigue) Early disseminated 3-12 wk erythemia (single or multiple), worse constitutional symptoms, cranial neuritis, meningitis, carditis, ocular disease Late 2 mo Arthritis. in lyme disease white blood cells can be elevated with range from 25,000 to 1 lakh /ml of predominently by polymorphonuclear cells. if syill in doubt for diagnosis of lyme disease you can go for ELISA screening test and also confirmatory test WESTERN BLOT TEST . these might help in diagnosis and treatment. where as multiple sclerosis can present with multiple symptoms ranging from pain , fatigue, to epilepsy and hemiplegia. for diagnosis MS mri scan is helpful hope i answered your query reagrds