Hi. Please let me know the complete LFT profile especially the SGPT and SGOT levels. Since he is HbeAg negative in most cases he would an inactive carrier ..however with high SGPT and SGOT we still need to be certain. For that we need to go for quantitative HBV DNA levels ..this tells us about the viral load
in the blood. If the viral load is high there are medications which can control the virus.
You also need to check him up for signs of chronic liver disease
.. test would include and ultrasound
, an Upper GI endoscopy to look for varices etc. A newer test Fibroscan (which is like an ultrasound) can detect the liver stiffness
without a biopsy .
As far as family is concerned they need to be screened for HbSAg (everyone including his wife, yourself, your parents, your siblings etc). If you'll are negative for HbsAg then you need to take Hepatitis B vaccine