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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Feeling Low, Sadness, Insecurity, Mood Swings. Have Stopped Taking Toperamate For Migraine. Is This A Withdrawal Sign?

hi i am 36 yr old female having a h\o migraine .am on tryptomer since 3 yrs ..was on 25 mg for quite a long time and then increased upto 50 since june 2011. but my migrine didnt get better and since august i have been taking toperamate 25 mg BD tryptomer 50 and magnesium citrate 400mg OD .by this medication my migraine is almost gone but since 1 month i am feeling ver very low, insecure ,and am always on the verge of crying. all the time i am crying. few days back i was fine with a certain situation but all of a sudden started feeling insecure . sometimes feel guilty and sometimes react in anger. my query is can this happen due to toperamate? is this depression ? should i increase tryptomer or stop toperamate? please advise me .
Thu, 11 Jul 2013
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Psychiatrist 's  Response
hi,
no it is not due to topiramate.
it is due to depression- as your symptoms are much disturbing to you my advise is to increase the dose of tryptomer gradually.

other best option is you take sertraline- 50mg or escitalopram-10mg for depression.

also continue topiramate for migraine..

if your symptoms are developed after any stressor then counseling is also required.

so consult any psychiatrist even after you have good response to above treatment, for further treatment planning.

dr r yadav
md psychiatry
yadavramashanker@gmail.com
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Feeling Low, Sadness, Insecurity, Mood Swings. Have Stopped Taking Toperamate For Migraine. Is This A Withdrawal Sign?

hi, no it is not due to topiramate. it is due to depression- as your symptoms are much disturbing to you my advise is to increase the dose of tryptomer gradually. other best option is you take sertraline- 50mg or escitalopram-10mg for depression. also continue topiramate for migraine.. if your symptoms are developed after any stressor then counseling is also required. so consult any psychiatrist even after you have good response to above treatment, for further treatment planning. dr r yadav md psychiatry yadavramashanker@gmail.com