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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Episodes Of Rigors At Night, Increased Urination, Severe Headaches, Muscle Soreness. Taking Zapril Since A Long Term. Help?

I m taking Zapril 5 mg and amlodipine besylate 10 mg for hypertension . Over the last few days I have developed rigors at night (very severe shaking and goosebumps all over), increased urination at night, severe headaches, muscle soreness and sharp stabbing pains all over. I don t feel good at all. I have been on these drugs for about five years and wondered if they had something to do with my symptoms. Now and again I feel quite faint especially when my blood pressure drops i.e. 97/57 yesterday. (My doctor gets me to monitor it at home).
Wed, 26 Dec 2012
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Cardiologist 's  Response
Hi there,
Thanks for writing in.
I am a qualified and certified cardiologist. I read your mail with diligence.
Kind of symptoms you described can occur with drug when you first begin to take these. As you are taking these for last 5 years it is unlikely to have symptoms. Have you been prescribed or have you started any over the counter medicines for any other problem that could be one reason. Your blood pressure as you have written also goes down to 97 mm Hg Systolic. Well the aim of BP drugs is to keep systolic between 110-120 mm Hg. All this need a review by your doctor. With passage of time need for taking BP drug do change both in dosage and frequency and t could change both ways that is you may need more drug or less drug therefore follow up with the doctor is necessary. Here you have additional symptoms for which there is no obvious explanation therefore I would urge to see your doctor and get the issues sorted out. Moreover, apart from physical examination investigations like lipid profile, EKG and Fasting blood sugar are periodically needed as we advance in age. Good Luck.
With Best Wishes

Dr Anil Grover
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Episodes Of Rigors At Night, Increased Urination, Severe Headaches, Muscle Soreness. Taking Zapril Since A Long Term. Help?

Hi there, Thanks for writing in. I am a qualified and certified cardiologist. I read your mail with diligence. Kind of symptoms you described can occur with drug when you first begin to take these. As you are taking these for last 5 years it is unlikely to have symptoms. Have you been prescribed or have you started any over the counter medicines for any other problem that could be one reason. Your blood pressure as you have written also goes down to 97 mm Hg Systolic. Well the aim of BP drugs is to keep systolic between 110-120 mm Hg. All this need a review by your doctor. With passage of time need for taking BP drug do change both in dosage and frequency and t could change both ways that is you may need more drug or less drug therefore follow up with the doctor is necessary. Here you have additional symptoms for which there is no obvious explanation therefore I would urge to see your doctor and get the issues sorted out. Moreover, apart from physical examination investigations like lipid profile, EKG and Fasting blood sugar are periodically needed as we advance in age. Good Luck. With Best Wishes Dr Anil Grover