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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Normalized Enzyme Level Indicate No Progression Of PBC?

Two years ago I was diagnosed with primary biliary cirrhosis. I am 48 yr old female caucasian. The literature in the last year shows something like 80% survival 20 yrs from diagnosis. I am taking Ursodiol and my enzymes have normalized. Is this reason to believe that my PBC is no longer progressing?
Wed, 9 Sep 2015
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General & Family Physician 's  Response
Hello,
Welcome to Health Care Magic. I read carefully your query and I understand your concern.
The primary biliary cirrhosis is an autoimmune disease that hasn’t yet known what exactly cause it and for this reason the treatment are focused on slowing the progress of disease, relieving symptoms and preventing complications. It has a slowly develop, especially when the treatment begin at early stage.
Ursodiol is a bile acid, doesn’t cure PBC but it normalize enzyme level and can slow the progress if it is starts at early stage disease.
I recommend you avoiding the bad habits like alcohol intake and smoking choose low-sodium foods and do a no sedentary life during all the time.
You should follow-up with the gastroenterologist and hepatologist during all live long.
Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions.
Kind regard,
Dr .Marsida Janko
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Does Normalized Enzyme Level Indicate No Progression Of PBC?

Hello, Welcome to Health Care Magic. I read carefully your query and I understand your concern. The primary biliary cirrhosis is an autoimmune disease that hasn’t yet known what exactly cause it and for this reason the treatment are focused on slowing the progress of disease, relieving symptoms and preventing complications. It has a slowly develop, especially when the treatment begin at early stage. Ursodiol is a bile acid, doesn’t cure PBC but it normalize enzyme level and can slow the progress if it is starts at early stage disease. I recommend you avoiding the bad habits like alcohol intake and smoking choose low-sodium foods and do a no sedentary life during all the time. You should follow-up with the gastroenterologist and hepatologist during all live long. Hope this answers your question. If you have additional questions or follow up questions then please do not hesitate in writing to us. I will be happy to answer your questions. Kind regard, Dr .Marsida Janko