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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Does Lexipro Reduce The Effects Of Tomaxifen?

I have been taking lexipro 20mg since sept last year. I was diagnosed with breast cancer June 2012 chemo, full mast, 25 rad, 12 months he reception. Started tomaxifen February 2013. What is your opinion on continuing on lexipro which can reduce effectiveness of tomaxifen? Very tired all the time, tink it s lexipro causing this. Also what is your opinion on removing ovaries as a preventative measure? Had her2positive grade 3 BC 8.2cm tumour, no nodes, clear margins, clear bone scan sept 2013. I would deeply worry bout this op due to hormone and psychological impact. Please advise.
Fri, 15 Feb 2019
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General & Family Physician 's  Response
Hi,

Lexapro is used for depression and anxiety which commonly occur with such diseases.

If you understand you feel fine and not depressed, you may talk to your doctor to gradually withdraw it.

Do not stop it suddenly on yourself. Regarding its effects on tamoxifen, it does not have any major interaction with Tamoifen, so don't worry about that.

I don't think you need to remove the ovaries, it's not recommended in breast cancers.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Mahboob Ur Rahman , General & Family Physician
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Does Lexipro Reduce The Effects Of Tomaxifen?

Hi, Lexapro is used for depression and anxiety which commonly occur with such diseases. If you understand you feel fine and not depressed, you may talk to your doctor to gradually withdraw it. Do not stop it suddenly on yourself. Regarding its effects on tamoxifen, it does not have any major interaction with Tamoifen, so don t worry about that. I don t think you need to remove the ovaries, it s not recommended in breast cancers. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Mahboob Ur Rahman , General & Family Physician