Hello, Thank you and pleased to answer you Tremor (hand shake), is one of the major signs of parkinson s disease. Tremor is part, along with akinesia and stiffness (or hypertonia) of the major symptoms of parkinson s disease. However, 25-50% of people with parkinson s disease show no tremor. In general, a tremor designates an involuntary and rhythmic movement. The latter is usually of low amplitude. There are several types of tremors: attitude tremor; essential ttremor; trembling action; rest tremor (fairly typical of parkinson s disease). If various tremors are found in certain pathologies, those of the parkinson disease can be identified because of their specific character. Thus, the tremor that intervenes in the disease of parkinson is a tremor called rest . Like all rest tremors, they diminish or even disappear during the movement. It most often touches a limb (arm or leg), in two thirds of the cases in the following order: hand, head, leg. It is asymmetrical (unilateral) although it tends to touch both sides of the body after a few years. It is particularly marked in case of stress. It disappears into action or when the person sleeps. But atypical forms may exist. The tremor action, also called intentional trembling , occurs only during voluntary movements (precise gestures such as holding a glass of water). It is more accentuated at the beginning and at the end of movement. This symptom is linked to various diseases or situations, such as: multiple sclerosis; the consequences of a cerebrovascular accident; a tumor, an infection or a degenerative atrophy, certain neuropathies. But as your husband is diabetic, and that vascular complications are the prerogative of diabetes. And that the stroke can be announced by a trembling of the hand, I believe that in front of the clinical picture of your husband, a cerebral Angioscanner is the first thing to do since the vital prognosis of your husband is put into play in case of a beginning ischemic stroke. I invite you to consult a cardiologist to eliminate a diabetic complication related to the cerebral vascular axes by the realization of a cerebral Angioscanner. If the ANGIOSCANNER is normal, we can check for Parkinson diseases. Best wishes.