I have been using trolamine salicylate Cvs Arthritis Cream. I applied some on my neck, shoulder,,hands and knee earlier this evening. After urniating I feel a slight cool feeling, also in my arm muscle and a cool feeling in my nose. I have had 2 other episodes in the past week or so with the cool feeling in my nose. I take Prednisone, Enbrel, Meloxacam, citilapram, acetimetophin, could I be having a reaction? Does this get to your system? Could it be that it isn t mixing with my medications?