It is a misconception the someone mixing something in drink will make her to land in such situation.
Sleep problems, irritability, dull look, not socializing, smoking
excessively etc can be suggestive of underlying some mental health issues like depression
, dissatisfaction with job or any personal issues etc
consultation will surely help
With available limited information, difficult to say that it can be passed from generation to generation. First we need to know that what exactly it is ?