Hi, Thank you for your query. I can understand your concerns. I feel your mom is suffering from Acalculous cholecystitis which may be seen with a variety of other systemic disease processes (sarcoidosis, cardiovascular disease).These co-morbidities can cause breathlessness. The setting of acute gallbladder inflammation complicating severe underlying illness is characteristic of acalculous disease.Ultrasound, CT abdomen usually demonstrates a large, tense, static gallbladder without stones and with evidence of poor emptying over a prolonged period . With the limited information you have provided, no other definite conclusion is difficult. Regards Dr. T.K. Biswas M.D. Mumbai