Thanks for visiting HCM.
Montoux test is not the diagnostic test always..many a times it is false negative. If chest xray is suggestive, it is better to go for sputum for acid fast bacilli examination for two samples, one of which must be early morning sample, to directly visualise the bacteria under microscope. If it is positive starting the therapy is mandatory. Even if the sputum test is negative and there is strong clinical or xray suspicion of tuberculosis
, it is always better to go for the treatment.
Taking a single dose will not make the bacteria drug resistant, so don't worry. And single dose will not alter the test result too.
If you have doubt on the diagnosis, better consult higher centres because mental satisfaction is also a must.
I think 500 mg of pyrazinamide
is just underdosing..so revise the dose.