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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Tramadol And Temazepam Be Taken Together?

I have three specialists treating me in addition to my primary care doctor: Cardiologist, pulmonary and oncology hematology. I also have a palliative care nurse who prescribes medicine. I check the interactions of drugs whenever I am prescribed a new drug. When the webMD site advises not to take Tramadol and Temazepam together -- does that simply mean that they can be taken an hour or two apart? The Xarelto warnings say not to take with NSAIDS, but the palliative care nurse said I could take Tramadol along with Aleve if needed. Since I take Xarelto, which warns against taking with NSAIDS, I m not sure how this affects the interactions. Please advise me.
Tue, 20 Feb 2018
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General & Family Physician,  's  Response
Hi & Welcome.

Tramadol and Temazepam should not be taken together.

Tramadol is an opioid (narcotic-like) pain reliever commonly prescribed for moderate to severe pain.

Temazepam is a short acting benzodiazepine commonly prescribed for sleep problems (insomnia) such as trouble falling asleep or staying asleep.

Taking Tramadol along with Temazepam can cause central nervous system depression which can lead to serious side effects including respiratory distress, coma, and even death.

You may need alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications.

Similarly taking NSAID like Aleve (Naproxen) together with Xarelto (Rivaroxaban)- 'a blood thinner' may increase the risk of bleeding, including severe and sometimes fatal hemorrhage.

You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness, red or black stools coughing up or vomiting fresh or dried blood that looks like coffee grounds.

Hope to have answered your queries.
Take care.
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Can Tramadol And Temazepam Be Taken Together?

Hi & Welcome. Tramadol and Temazepam should not be taken together. Tramadol is an opioid (narcotic-like) pain reliever commonly prescribed for moderate to severe pain. Temazepam is a short acting benzodiazepine commonly prescribed for sleep problems (insomnia) such as trouble falling asleep or staying asleep. Taking Tramadol along with Temazepam can cause central nervous system depression which can lead to serious side effects including respiratory distress, coma, and even death. You may need alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Similarly taking NSAID like Aleve (Naproxen) together with Xarelto (Rivaroxaban)- a blood thinner may increase the risk of bleeding, including severe and sometimes fatal hemorrhage. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness, red or black stools coughing up or vomiting fresh or dried blood that looks like coffee grounds. Hope to have answered your queries. Take care.