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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Metformin Elevate Gamma GT Levels?

Does Metformin raise Gamma GT levels? I ve been taking 500mg Metformin twice a day for PCOS for approx 4-5 months and my Gamma GT and Serum ALT levels have continued to increase over the same time period. Gamma GT is currently 132iU/L and Serum ALT is 74iU/L. Thanks
Fri, 24 Apr 2020
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General & Family Physician 's  Response
Hi,

Metformin is unlikely to be the cause. The common side effects of metformin include abdominal cramps, diarrhea, vitamin B-12 deficiency and a less common but serious condition lactic acidosis. Based on the results of lab test, liver injury does not seem to be due to metformin.

Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Mohammed Taher Ali, General & Family Physician
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Can Metformin Elevate Gamma GT Levels?

Hi, Metformin is unlikely to be the cause. The common side effects of metformin include abdominal cramps, diarrhea, vitamin B-12 deficiency and a less common but serious condition lactic acidosis. Based on the results of lab test, liver injury does not seem to be due to metformin. Hope I have answered your question. Let me know if I can assist you further. Regards, Dr. Mohammed Taher Ali, General & Family Physician