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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Can Hydroxychloroquine Cause Sphincter Of Oddi Dysfunction?

Can hydroxychloroquine cause sphincter of Odie dysfunction. My first month on Plaquenil. Sphincter of Oddi has been great for four years using Zen pep and artichoke capsules with every meal. Now it s back and I realized the first time I ever got sphincter of Oddi , I was 4 aweeks after being on malaria medicine for a two week trip to India in 2005 .
Wed, 22 Apr 2020
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General & Family Physician,  's  Response
Hi,

Hydroxychloroquine is commonly prescribed to treat rheumatoid arthritis, malaria and other autoimmune diseases.

Generally it is very well tolerated. Its common side effects include nausea and diarrhea, which often improve with time.

Other side effects are skin rash, changes in skin pigment, hair changes, muscle weakness, visual disturbances, and anemia (in individuals with G6PD deficiency or porphyria).

There is no documented evidence that it affects the normal contraction and relaxation of sphincter of Oddi.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr. Mohammed Taher Ali
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Can Hydroxychloroquine Cause Sphincter Of Oddi Dysfunction?

Hi, Hydroxychloroquine is commonly prescribed to treat rheumatoid arthritis, malaria and other autoimmune diseases. Generally it is very well tolerated. Its common side effects include nausea and diarrhea, which often improve with time. Other side effects are skin rash, changes in skin pigment, hair changes, muscle weakness, visual disturbances, and anemia (in individuals with G6PD deficiency or porphyria). There is no documented evidence that it affects the normal contraction and relaxation of sphincter of Oddi. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr. Mohammed Taher Ali