The natural history and prognosis of COPD are variable and incompletely understood. They probably depend upon a number of factors including genetic predisposition, environmental exposures, comorbidities. A number of factors have been identified as prognostic indicators for COPD. Additional predictors of accelerated lung function decline, diminished physical function, and/or mortality in patients with COPD include
Airways responsiveness, Cigarette smoking
, Low body-mass index (BMI ≤21), HIV infection, Increased airway bacterial load, Decreased exercise capacity, Peak oxygen
consumption (VO2), , Elevated C-reactive protein
(>3 mg/L), Male gender, Chest computed tomography
showing presence of emphysema
I think you should quit smoking "its enough"