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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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CML Patient. Diabetic. Body Rashes After Stopping Wysolone. Continue Wysolone?

Hello, My father is CML patient, in initial phase, and he s also patient of Diabetes(24 yrs), sugar fluctuates almost daily( insulin dosage 20 units along with medicines glycomate, glider). He is taking wysolone 5 mg for about 2 months now since he had severe reaction of imatinib.. he stopped taking medicine for 2-3 days and now he having body rashes again.. can you please if he has to continue wysolone for few more months..if yes how can he control the sugar..
Mon, 13 May 2013
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General & Family Physician 's  Response
Hi. Your father is having severe reaction to Imatinib and he needs to take Prednisolone for it. Secondly he is diabetic and his sugars may worsen because of wysolone. Hence it is advisable that he changes his CML drug to second line drugs like Nilotinib or Dasatinib. They are more potent drugs too but costly.
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CML Patient. Diabetic. Body Rashes After Stopping Wysolone. Continue Wysolone?

Hi. Your father is having severe reaction to Imatinib and he needs to take Prednisolone for it. Secondly he is diabetic and his sugars may worsen because of wysolone. Hence it is advisable that he changes his CML drug to second line drugs like Nilotinib or Dasatinib. They are more potent drugs too but costly.