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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Brown Spots On Feet, Kidney Issues, Diabetes. On Dialysis. Used Cream. Cause?

Hi Doctor.My name is Emilia and I'm interesting about my problem with brown spots on my feet.There is something what can help or treat?
I have diabetes 21 years already.They show up before 9 months when start my kidneys problem. Then I started to do dialyses.The doctor gave me some cream,but doesn't help me.Please if you have some answer,advice me what to do,because I'm very concern about my situation.Thank you.
Fri, 26 Apr 2013
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General & Family Physician 's  Response
Hello,
Since you are a diabetic and undergoing dialysis,it means you are suffering from end stage renal disease ( ESRD ).
It is very common to find pigmentary changes in the  skin of patients suffering from ESRD.
It is noted  that 25-70% of dialysis patients are affected to some degree. Incidence increases with the duration of renal disease. The spectrum of pigmentary changes ranges from hyperpigmentation to yellowish discolouration and pallor. Hyperpigmentation is often photodistributed and is the result of an increase in melanin in the basal layer of the epidermis. The yellow skin colour in ESRD patients is caused by lipochrome and carotenoid deposition in the dermis and subcutaneous tissues. Pallor is also as a result of anemia associated with renal failure.
Although treatments like emollients and moisturisers are given,but they rarely have any affect,as in you.However renal transplant is supposed to be ultimate curative for not only hyperpigmentaion but also any pruritis,if associated.
Thanks
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Cardiologist Dr. Anantharamakrishnan's  Response
Hi friend,
Welcome to Health Care Magic

Either Renal failure or Diabetes may be responsible...and can only improve, when they are controlled well...
Considering the long duration, local applications may not be helpful.
Vasculitis is probably the underlying cause
An opinion from dermatologist will be helpful...

Take care
Wishing speedy recovery
God bless
Good luck
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Brown Spots On Feet, Kidney Issues, Diabetes. On Dialysis. Used Cream. Cause?

Hello, Since you are a diabetic and undergoing dialysis,it means you are suffering from end stage renal disease ( ESRD ). It is very common to find pigmentary changes in the  skin of patients suffering from ESRD. It is noted  that 25-70% of dialysis patients are affected to some degree. Incidence increases with the duration of renal disease. The spectrum of pigmentary changes ranges from hyperpigmentation to yellowish discolouration and pallor. Hyperpigmentation is often photodistributed and is the result of an increase in melanin in the basal layer of the epidermis. The yellow skin colour in ESRD patients is caused by lipochrome and carotenoid deposition in the dermis and subcutaneous tissues. Pallor is also as a result of anemia associated with renal failure. Although treatments like emollients and moisturisers are given,but they rarely have any affect,as in you.However renal transplant is supposed to be ultimate curative for not only hyperpigmentaion but also any pruritis,if associated. Thanks