wellcome mr Boller
well before replying to your query i have few question as how long you hv been hypertensive? Diabetes status r previous cardiac event and joint pain and deformity
and your current renal status( serum BUN, creatinine
well for the allopurinol
dosing you should consult to your doc, as you may need to increase the dose of allopurinol as the initial dose is usually 300mg PO daily. daily doses can be increased by 100mg every 2 to 4 week to achieve the minimum maintenence dosage that will keep the uric acid level below 6mg/dl,( and care must be taken in renal and hepatic impairement in dose adjusment of allopurinol)
for the hyperaggregation you also need to start with the platelet aggregation inhibitor agent like aspirin , clopidogrel
. .etc but with proper assesment so consult ur doc and get help as you need proper multi disciplinary assesment. hope that it would be helpful.