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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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Blood Test Done, High Creatine Kinase, Prescribed Cholesterol Lowering Medication. Suggestion?

My mother has just had a blood test and her Creatine Kinase (CK) levels are very high. Her doctor has suggested that the cholesterol lowering medication she is on could be the cause. I cannot find any information that suggests it could be caused this way. From what I can see it all relates to muscle damage. Could you give me your opinion?
Thu, 10 Oct 2013
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Orthopaedic Surgeon, Joint Replacement 's  Response
Hi, thanks for writing to HCM.

The enzyme Creatine kinase levels will be elevated in blood when there is muscle damage. This can occur in cardiac problems (myocardial infarction) and in skeletal muscle damage.

Propably your mother might be taking some STATIN preparation (Atorvastatin or Rosuvastatin) to lower her cholesterol levels. The most common side effects with these drugs is Myalgias (painful muscles), which is not so concerning. But at times, they may produce serious muscle damage (Rhabdomyolysis) which may result in Renal failure. In this setting, the blood levels of Creatine kinase are very much elevated. So, for this reason your treating doctor might have ordered to stop the cholesterol lowering drug (especially Statins).

Hope this information is helpful. Good day
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Blood Test Done, High Creatine Kinase, Prescribed Cholesterol Lowering Medication. Suggestion?

Hi, thanks for writing to HCM. The enzyme Creatine kinase levels will be elevated in blood when there is muscle damage. This can occur in cardiac problems (myocardial infarction) and in skeletal muscle damage. Propably your mother might be taking some STATIN preparation (Atorvastatin or Rosuvastatin) to lower her cholesterol levels. The most common side effects with these drugs is Myalgias (painful muscles), which is not so concerning. But at times, they may produce serious muscle damage (Rhabdomyolysis) which may result in Renal failure. In this setting, the blood levels of Creatine kinase are very much elevated. So, for this reason your treating doctor might have ordered to stop the cholesterol lowering drug (especially Statins). Hope this information is helpful. Good day