The report has confirmed Tuberculosis
of bone which requires at least 12-18 months of ATT course so it is necessary to get a TB PCR and AFB culture done to get an immediate response of the specific drugs that can be started following the culture reports. However AKT4
is very effective but is broad spectrum, so much so that in two months all the TB reports will be negative. But if the Tubercle bacilli is not of the strain identified in the culture then it could relapse and combination of the drugs will have to be changed and the treatment might have to be prolonged.
AFB culture with drug sensitivity gives you the exact drugs sensitivity which will be effective for the specific bacilli found.
Please note in most of the cases AKT4 is effective and shows a good response but if advanced techniques are available then why not go for it .