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Dr. Andrew Rynne
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Dr. Andrew Rynne

Family Physician

Exp 50 years

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35 Weeks Pregnant, Severe Itching, Alkaline Phosphatase Level 298, Solution ?

I am 35 weeks 5 days pregnant.I have severe itching from 32 weeks.In my Liver Function test Alkaline Phosphatase level is increasing every time.In Lab kit its normal range is 44-126 but in my case last week it has become 298 and i am itching like mad all over body.I am taking udiliv 300 twice a day but no effect
Thu, 10 May 2012
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Pathologist and Microbiologist,  's  Response
Hello. Welcome to HCM.
Itching in late part of pregnancy is due to increasing pressure of gravid uterus on biliary system, leading to transient cholestasis. Bile salt deposition leads to itching. It may be unnerving to hear, that for most people, nothing helps, only after 36th week, there might be relief when uterus descends.
However, a few drops of savlon like antiseptic might be helpful. Avoid skiin dryness otherwise, by using soothening moisturisers.
ALP elevates in pregnancy because of cholestasis and also because PLACENTA is a SOURCE OF PRODUCTION OF ALP, unlike non-pregnant persons.
So, dont worry. Enjoy this period.
take care
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35 Weeks Pregnant, Severe Itching, Alkaline Phosphatase Level 298, Solution ?

Hello. Welcome to HCM. Itching in late part of pregnancy is due to increasing pressure of gravid uterus on biliary system, leading to transient cholestasis. Bile salt deposition leads to itching. It may be unnerving to hear, that for most people, nothing helps, only after 36th week, there might be relief when uterus descends. However, a few drops of savlon like antiseptic might be helpful. Avoid skiin dryness otherwise, by using soothening moisturisers. ALP elevates in pregnancy because of cholestasis and also because PLACENTA is a SOURCE OF PRODUCTION OF ALP, unlike non-pregnant persons. So, dont worry. Enjoy this period. take care