Brief Answer:
yes, it can

Detailed Answer:
Hi,

Thanks for your query.

Yes, leprosy can come back even after MDT. This could be due to a more resistant variant of the bacteria. In these cases, the agents in the MDT will be changed to higher ones with a better curing power.

Sometimes even a culture sensitivity test is performed to see whether the bacteria can be killed by the specific antibiotic agent which can be incorporated in MDT regimen.

There are numerous other factors which can influence the recurrence eof the disease like, immunity, diet, exercise, compliance with medications etc. All the influencing factors must be well thought of and managed.

Hope, I answered your query.

Wish you good health.

Regards,

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