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What Medications Can Cause Liver Lesions?

Posted on Fri, 25 Jul 2014

Question: Can certain medications cause Liver Lesions & if so what are the medications?

Answered by Dr. Vidya KR (1 hour later)

Brief Answer:
Yes many drugs do affect liver

Detailed Answer:
Hi, thanks for using Healthcaremagic.

Yes medications do have effect on liver. Many drugs affect the liver to one degree or another degree. new drugs are always being approved for general use.

Different drugs cause different effect on liver.
Drugs that may cause ACUTE FATTY INFILTRATION OF THE LIVER
adrenocortical steroids
phenothiazines
sulfonamides
antithyroid drugs
phenytoin
tetracycline
isoniazid
salicylates
valproic acid
methotrexate

Drugs that may cause CHOLESTATIC JAUNDICE
erythromycin
amoxicillin/clavulanate
cloxacillin flecainide
azathioprine
cyclophosphamide
flurazepam
captopril
cyclosporine
carbamazepine
sulfonamides
oral contraceptives
tamoxifen
methyltestosterone
nifedipine
penicillamine
tolbutamide
nitrofurantoin
phenothiazines
tricyclic antidepressants
anti-inflammatory drugs

Drugs causing LIVER TUMOR
anabolic steroids
oral contraceptives
thorotrast
danazol
testosterone

This list is a general list but there are many drugs affecting liver.

Hope I answered your query. Feel free to ask further related query.

Regards

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Vidya KR (19 hours later)

We don't know the proper name for THORAZINE OR IF THAT IS THE PROPER NAME, however about 2 or 3 years ago his liver Enzymes were all OUT OF WACK!! So his regular Dr. Sent him to an oncologist hematologist he did more blood work & at this time his blood work came back ok, but I had taken him to the EMERGECY Room about 2wks BEFOR with pain & that Dr. Told him to stop taking the THORAZINE, which he did, but not long after the Dr's found a liver Leisons. So there for we want to know CAN THORAZINE CAUSE LIVER LEISONS?????? PLEASE WE REALLY NEED TO KNOW ABOUT THIS, ASAP!! Thank You So Much for your help in this Matter, God Bless You & Yours

Answered by Dr. Vidya KR (3 hours later)

Brief Answer:
Yes Chlorpromazine has effect on liver

Detailed Answer:
Hi, Thanks for follow up query.

Thorazine contains Chlorpromazine, it has effect on liver. It can result in raised liver enzymes and Jaundice.
Presence of any liver abnormality needs to discontinue this medication.

Hope i answered your query. Feel free to ask further related query.

Regards

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar