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What Is The Difference Between Painless Vaccination And A Normal One?

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Posted on Mon, 12 Jan 2015
Question: what is the difference between painless vaccination and a normal one. XXXXXXX got his second vaccination as painless IPV/DPT/HIB yesterday. He is not able to sleep properly and feeling uneasy..there is no fever
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Answered by Dr. Diptanshu Das (38 minutes later)
Brief Answer:
Painful vaccines are whole cell vaccines

Detailed Answer:
Thanks for asking on Healthcare Magic.

The conventional painful pertussis vaccines (DTwP) contained cellular components of dead bacteria which was responsible for reactions and hence the pain.
The painless vaccines (DTaP) are acellular and hence are called painless as they cause less reaction, hence less pain.
In case of the painful vaccine i.e. DTwP vaccine where the w stands for whole cell, meaning it is made up of the entire cell of the deactivated organism , the Pertusis part of the vaccine has been associated with side effects such as pain, fever and irritability due to the presence of certain cellular components that cause reactions. But such reactions do not occur in case of the DTaP vaccine, the “a” stands for acellular, meaning it is made with the parts of the Pertusis bacteria, and hence the pain is quite less.

This vaccine is administered in combination with injectable polio vaccine and Hemophilus influenzae B vaccine.

Probably the child is unable to sleep properly due to the slight pain and discomfort of the vaccination. In case you feel that he might be in pain, you may give a dose or two of paracetamol (crocin) which is otherwise given for fever. You need not worry. It should subside in a day or so and things would be fine.

Hoping your family to be fit and fine

Regards

Note: For further queries related to your child health, Talk to a Pediatrician. Click here to Book a Consultation.

Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju
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Answered by
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Dr. Diptanshu Das

Pediatrician

Practicing since :2005

Answered : 3875 Questions

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What Is The Difference Between Painless Vaccination And A Normal One?

Brief Answer: Painful vaccines are whole cell vaccines Detailed Answer: Thanks for asking on Healthcare Magic. The conventional painful pertussis vaccines (DTwP) contained cellular components of dead bacteria which was responsible for reactions and hence the pain. The painless vaccines (DTaP) are acellular and hence are called painless as they cause less reaction, hence less pain. In case of the painful vaccine i.e. DTwP vaccine where the w stands for whole cell, meaning it is made up of the entire cell of the deactivated organism , the Pertusis part of the vaccine has been associated with side effects such as pain, fever and irritability due to the presence of certain cellular components that cause reactions. But such reactions do not occur in case of the DTaP vaccine, the “a” stands for acellular, meaning it is made with the parts of the Pertusis bacteria, and hence the pain is quite less. This vaccine is administered in combination with injectable polio vaccine and Hemophilus influenzae B vaccine. Probably the child is unable to sleep properly due to the slight pain and discomfort of the vaccination. In case you feel that he might be in pain, you may give a dose or two of paracetamol (crocin) which is otherwise given for fever. You need not worry. It should subside in a day or so and things would be fine. Hoping your family to be fit and fine Regards