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What Does Urine Test Showing Hyaline Casts Indicate?

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Posted on Wed, 24 Jun 2015
Question: My urine test shows occas hyaline cast in comments. Can you explain what this means, please? Thanks
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Answered by Dr. Harish Naik (1 hour later)
Brief Answer:
Hyaline casts is usually not clinically significant.

Detailed Answer:
Hello and thanks for your query.

I shall make an effort to provide you with good professional recommendations specific to your questions.

Hyaline casts are formed by protein, which has precipitated inside of individual tubule lumens. This protein is secreted by cells in the thick ascending limb. It has a peculiar characteristic of aggregating to form a gel when it is concentrated in urine. If there’s nothing else around when it gels, it forms these hyaline casts. Accordingly I would say, hyaline cast are normal and only indicate that the patient may have had somewhat concentrated urine at the time it was collected.

However hyaline casts are sometimes formed due to dehydration, exercise, or (water pills) diuretic medicines. None of thees are going to trouble you. So do not be worried.

In the nutshell, hyaline casts are clinically non-significant finding.

Yet again, I duly appreciate your query to me, I do hope that you have found something useful to help you and I shall be glad to answer any further apprehensions.

Sincerely,
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Above answer was peer-reviewed by : Dr. Prasad
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Answered by
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Dr. Harish Naik

General & Family Physician

Practicing since :2008

Answered : 2635 Questions

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What Does Urine Test Showing Hyaline Casts Indicate?

Brief Answer: Hyaline casts is usually not clinically significant. Detailed Answer: Hello and thanks for your query. I shall make an effort to provide you with good professional recommendations specific to your questions. Hyaline casts are formed by protein, which has precipitated inside of individual tubule lumens. This protein is secreted by cells in the thick ascending limb. It has a peculiar characteristic of aggregating to form a gel when it is concentrated in urine. If there’s nothing else around when it gels, it forms these hyaline casts. Accordingly I would say, hyaline cast are normal and only indicate that the patient may have had somewhat concentrated urine at the time it was collected. However hyaline casts are sometimes formed due to dehydration, exercise, or (water pills) diuretic medicines. None of thees are going to trouble you. So do not be worried. In the nutshell, hyaline casts are clinically non-significant finding. Yet again, I duly appreciate your query to me, I do hope that you have found something useful to help you and I shall be glad to answer any further apprehensions. Sincerely,