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What Does The Following Microalbumin Report Indicate?

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Posted on Fri, 29 May 2015
Question: Hi,
I am XXXX, 36 years old. Las year I was diagnosed as pre diabetic. However, I controlled my sugr by diet and by reducing weight.
My recent Hb1AC is 51.
Recently I got my following tests done.
Serum Creatinie 1 mg/dl
Urea 14
Urine Routine protiens NIL.
Doctor also advised me to get Microalbumine Urine done.
Following are the results of Microalbimun Urine (Spot):
Albumin : 30 mg/L
Cretinine : 200 mg/DL
A:C ratio : <30 mg/g

I would like to know if my microalbumin report is normal? What does albumin of 30 mg/l signify in this report? Is it normal to get this much albumin? Is it detected for all? Thanks


doctor
Answered by Dr. Dr. Abhay A Mali (51 minutes later)
Brief Answer:
Absolutely normal reports.

Detailed Answer:
Hi Mr. XXXX,
It is really appreciated that you have reverted your pre-diabetic status (HbA1c level 5.7 to 6.4) to normal (HbA1c <5.7) with diet and reducing weight.

What are the test results you have mentioned in question are normal

Usually spot urinary albumin alone is not of help in estimating nephropathy.
Spot Urinary albumin need to be estimated with urinary creatinine, ratio of which (Albumin : Creatinine) gives better estimate of nephropathy.
Interpretation of result as follow:
Normal: < 30 mg/g
Microalbuminuria: 30–299 mg/g
Macro (clinical) albuminuria: > 300 mg/g.

Spot Urine albumin usually absent in healthy adult but it may be increased in certain situations like after exercise, fever in pregnant woman.

Rather than spot urinary albumin, 24 hour urinary albumin is of more value for estimating nephropathy.
Interpretation of result as follow:
Normal: < 30 mg/24hrs
Microalbuminuria: 30–299 mg/24hrs
Macro (clinical) albuminuria: > 300 mg/24hrs.

Hope this may have cleared your queries.
If you have further question I will be happy to help.

Regards,
Dr. Abhay Mali.
Diabetologist.
Above answer was peer-reviewed by : Dr. Neel Kudchadkar
doctor
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Follow up: Dr. Dr. Abhay A Mali (37 minutes later)
Thanks a lot Doctor for your reply.
As you said that Albumin is generally absent in healthy adults then having albumin in my report is abnormal? If no then is it a normal value to have Albumin of 30 mg/L. As I read on the net, it is written that Albumin should be less than 30 mg/L but mine is 30 mg/L. Or this value is insignificant ?
Also, as you said that Albumin is generally absent in healthy adults the how the A:C ration is calculated if there is no Albumin in spot urine.?
I am sorry to ask so many questions but I am really worried about this.
Also I am at a high risk of having kidney problem in future.
doctor
Answered by Dr. Dr. Abhay A Mali (6 hours later)
Brief Answer:
I wouldn't be concerned.

Detailed Answer:
Hi Mr. XXXXXXX

Normal value for spot urinary albumin is 0 to 30mg/l.
Normal value for spot urinary albumin creatinine ratio is 0 to 30mg/g (ratio in your case is 15)
To compensate for variations in urine concentration in spot-check samples, it is helpful to compare the amount of albumin in the sample against concentration of creatinine that is albumin/creatinine ratio (ACR).

All your values are in limits. Value of 30 to 299mg/l for spot urinary albumin or value of 30 to 299mg/g for spot urinary albumin creatinine ratio is considered as microalbuminuria. Further microalbuminuria is a predictor of future kidney disease, it is a reversible state.

Usually in prediabetes, microalbuminuria is a predictor of glycemic control; that is microalbuminuria is associated with increased risk of progression to diabetes from prediabetes. Therefore at this point, I wouldn't be overly concerned. However I will suggest you follow up with your local physician/diabetes for further assessment/evaluation if needed.

I think this may have clarified your queries.
If so you can close the discussion and rate the answer.

Regards,
Dr. Abhay Mali
Note: For further follow-up, discuss your blood glucose reports with our diabetologist. Click here.

Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
Dr.
Dr. Dr. Abhay A Mali

Diabetologist

Practicing since :2006

Answered : 807 Questions

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What Does The Following Microalbumin Report Indicate?

Brief Answer: Absolutely normal reports. Detailed Answer: Hi Mr. XXXX, It is really appreciated that you have reverted your pre-diabetic status (HbA1c level 5.7 to 6.4) to normal (HbA1c <5.7) with diet and reducing weight. What are the test results you have mentioned in question are normal Usually spot urinary albumin alone is not of help in estimating nephropathy. Spot Urinary albumin need to be estimated with urinary creatinine, ratio of which (Albumin : Creatinine) gives better estimate of nephropathy. Interpretation of result as follow: Normal: < 30 mg/g Microalbuminuria: 30–299 mg/g Macro (clinical) albuminuria: > 300 mg/g. Spot Urine albumin usually absent in healthy adult but it may be increased in certain situations like after exercise, fever in pregnant woman. Rather than spot urinary albumin, 24 hour urinary albumin is of more value for estimating nephropathy. Interpretation of result as follow: Normal: < 30 mg/24hrs Microalbuminuria: 30–299 mg/24hrs Macro (clinical) albuminuria: > 300 mg/24hrs. Hope this may have cleared your queries. If you have further question I will be happy to help. Regards, Dr. Abhay Mali. Diabetologist.