Sign-in to Ask A Doctor - 24x7
OR
Sign in with Google
What Does The Following Biopsy Report Indicate?
Question: sir i am a patient of oral submucous fibrosis..biopsy report is as follows...
the sections stained with h&e revealed the presence of hyperkeratotic,atrophic surface epithelium with flattering of rete ridges.
the sub epithelial connective reveals the presense of densely packed hyalanised collagen fibres,reduction in numbers od fibroblasts and blood capillaries,specially in the lamina propria region.
no feature of any malignancy could be detected in any of the region.no my question is
1.is there any dysplasia noted?
2.can i take limited alcohol i.e one time in one month?i completely give up tobacco and smoking?
3.is there any chance of cancer in future?
the sections stained with h&e revealed the presence of hyperkeratotic,atrophic surface epithelium with flattering of rete ridges.
the sub epithelial connective reveals the presense of densely packed hyalanised collagen fibres,reduction in numbers od fibroblasts and blood capillaries,specially in the lamina propria region.
no feature of any malignancy could be detected in any of the region.no my question is
1.is there any dysplasia noted?
2.can i take limited alcohol i.e one time in one month?i completely give up tobacco and smoking?
3.is there any chance of cancer in future?
Brief Answer:
No dysplasia at present; need regular follow up.
Detailed Answer:
Hello dear, welcome to HCM forum.
Thanks for posting to us.
I have gone through your query and understand your concerns.
I will try to answer your question in the same order:
1) In the present histopathology, there are no signs of dysplasia mentioned.
2) Tobacco (smoking/chewing) should be definitely avoided. If possible, it is better to totally abstain from alcohol too as these will promote carcinogenesis through free radical injury at cellular level (tobacco>>>alcohol).
3) Though submucous fibrosis per se is not considered a premalignant lesion (still debates are ongoing in this regard), individuals with this have a higher than normal incidence of oral cancer. So we need regular follow up with clinical examination.
Hope I have answered your queries.
If you have further questions, I will be happy to help.
Wishing you good health
Thank you.
No dysplasia at present; need regular follow up.
Detailed Answer:
Hello dear, welcome to HCM forum.
Thanks for posting to us.
I have gone through your query and understand your concerns.
I will try to answer your question in the same order:
1) In the present histopathology, there are no signs of dysplasia mentioned.
2) Tobacco (smoking/chewing) should be definitely avoided. If possible, it is better to totally abstain from alcohol too as these will promote carcinogenesis through free radical injury at cellular level (tobacco>>>alcohol).
3) Though submucous fibrosis per se is not considered a premalignant lesion (still debates are ongoing in this regard), individuals with this have a higher than normal incidence of oral cancer. So we need regular follow up with clinical examination.
Hope I have answered your queries.
If you have further questions, I will be happy to help.
Wishing you good health
Thank you.
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
please tell me about good diet chart which will helpfull for me..
Brief Answer:
Include more fruits and veges.
Detailed Answer:
Hi dear,
Regarding diet, there is no specific guidelines defined.
It will be fine if you cut down proportion of fried items, smoked food, and fast food items(which are rich in free radicals) in your diet.
Also include plenty of fruits and green leafy veges (which are rich in antioxidants and free radical scavengers).
Wishing you good health.
Thank you.
Include more fruits and veges.
Detailed Answer:
Hi dear,
Regarding diet, there is no specific guidelines defined.
It will be fine if you cut down proportion of fried items, smoked food, and fast food items(which are rich in free radicals) in your diet.
Also include plenty of fruits and green leafy veges (which are rich in antioxidants and free radical scavengers).
Wishing you good health.
Thank you.
Above answer was peer-reviewed by :
Dr. Bhagyalaxmi Nalaparaju
atlast please tell me that is osf fully curable?thanking you...
Brief Answer:
Difficult to completely cure it.
Detailed Answer:
Hello dear,
Submucus fibrosis, once formed is actually difficult to treat and cure completely.
But, symptoms like difficulty in opening mouth, difficulty in tongue movement etc., can be treated symptomatically. In the initial stages these are treated with intralesional injection of steroids etc. Advanced cases may need surgical excision and grafting.
Avoiding further exposure to causative agents like tobacco may help to prevent or slow down further progression.
Let's hope for the best.
Take care.
Thank you.
Difficult to completely cure it.
Detailed Answer:
Hello dear,
Submucus fibrosis, once formed is actually difficult to treat and cure completely.
But, symptoms like difficulty in opening mouth, difficulty in tongue movement etc., can be treated symptomatically. In the initial stages these are treated with intralesional injection of steroids etc. Advanced cases may need surgical excision and grafting.
Avoiding further exposure to causative agents like tobacco may help to prevent or slow down further progression.
Let's hope for the best.
Take care.
Thank you.
Note: Consult an experienced Otolaryngologist / ENT Specialist online for further follow up on ear, nose, and throat issues - Book a Call now.
Above answer was peer-reviewed by :
Dr. Ashwin Bhandari
Answered by
Get personalised answers from verified doctor in minutes across 80+ specialties
