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What Does Positive ANA Indicate?

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Posted on Tue, 27 May 2014
Question: I have had a blood test done and the doctor came back with positive ana so he has ordered ENA ds DNA to rule out Lupus can you have something not as serious as this with positive ANA
doctor
Answered by Dr. Divya Agarwal (35 minutes later)
Brief Answer:
A positive ANA may be present in 10% of normal peo

Detailed Answer:
hello,
There is no significance of having a positive ANA test without any of the symptoms suggesting lupus.
Also it is much more important to have a positive ANA by indirect immunofluorescence.
Also ENA is generally positive in significant titers only in the presence of lupus.
So your clinical symptoms like arthritis, rash, oral ulcers, raynauds, pleurisy etc indicate the significance of a positive ANA.
positive ANA may be present in 10% of people without any symptoms of lupus.
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Above answer was peer-reviewed by : Dr. Vinay Bhardwaj
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Answered by
Dr.
Dr. Divya Agarwal

Rheumatologist

Practicing since :1999

Answered : 659 Questions

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What Does Positive ANA Indicate?

Brief Answer: A positive ANA may be present in 10% of normal peo Detailed Answer: hello, There is no significance of having a positive ANA test without any of the symptoms suggesting lupus. Also it is much more important to have a positive ANA by indirect immunofluorescence. Also ENA is generally positive in significant titers only in the presence of lupus. So your clinical symptoms like arthritis, rash, oral ulcers, raynauds, pleurisy etc indicate the significance of a positive ANA. positive ANA may be present in 10% of people without any symptoms of lupus.